Meridia (sibutramine hydrochloride monohydrate) is prescribed to achieve and maintain weight loss in obese patients. It is intended and recommended for patients with a body mass index (BMI) greater than 30, or 27 if other health risks are present. Like most medications, some side effects are possible if you take Meridia.
Function
Meridia works by inhibiting the reuptake of the neurotransmitters serotonin, dopamine and norepinephrine, which are chemicals of the brain that affect hunger.
Common Side Effects
Common side effects include sleep disruption, dry mouth, headache, loss of appetite and constipation.
Serious Side Effects
Serious side effects that have been reported include seizures, bleeding, an increase in blood pressure or heart rate, and a rare condition called "serotonin syndrome," which can be life threatening. According to the Food and Drug Administration, reported allergic reactions include hives, angioedema and anaphylaxis.
Warning
According to the FDA, blood pressure and/or pulse rate can significantly increase in some patients. Blood pressure and pulse rate should be monitored while taking Meridia.
Consideration
Meridia is classified and controlled as a Schedule IV drug under the Controlled Substances Act. Abuse may lead to limited physical or psychological dependence.